Two cars each carrying two people crashed at 1542 Mountainview Drive in Haycock Township (Bucks County) around 11:40 p.m., Pennsylvania State Police said.
Initial reports say the vehicles caught fire after crashing head-on.
The driver of a Chevrolet Equinox, a 26-year-old man from Ossining, NY, was airlifted with serious injuries. His passenger, an unidentified 24-year-old woman from Rockaway, NJ, died.
The two occupants of the Lexus ES 330 both died, and they were identified as 25- and 26-year-old men from Ottisville and Quakertown, PA.
PSP Troop M Dublin Barracks was investigating with assistance from Troop M Collision Analysis Reconstruction Unit and Troop M Forensic Service Unit.
Click here to follow Daily Voice Paramus and receive free news updates.